ESPResSo++ is a software package for the scientific simulation and analysis of coarse-grained atomistic or bead-spring models as they are used in soft matter research. ESPResSo++ has a modern C++ core and flexible Python user interface. ESPResSo and ESPResSo++ have common roots however their development is independent and they are different software packages. ESPResSo++ is free, open-source software published under the GNU General Public License (GPL)