The interdisciplinary and intersectoral virtual workshop “Micromechanics, statistics, and hazards of mechanical failure” aims to establish a common understanding of the theoretical foundations and the practical characterization of avalanche phenomena and failure in mechanical systems, stimulating new interdisciplinary collaborations between professionals and scholars working in different areas and contexts. We invite contributions on the study of: transformation events in crystalline and amorphous solids; fracture in heterogeneous materials and rocks; structural failure of engineered constructions; rock-falls, landslides and snow avalanches; natural and anthropogenic seismicity, and any other processes related to mechanical failure. This workshop is sponsored by the AXA Research Fund, through the project RehMechFail.